Nebita 5mg Tablet

✔️ Uses of Nebita 5mg Tablet

Hypertension

✔️ How does Nebita 5mg Tablet work?

works specifically on the heart by slowing down the heart rate and making the heart more efficient at pumping blood around the body. This results in lowering down of the blood pressure.

✔️ Side Effects of Nebita 5mg Tablet

Some common side effects of Nebivolol may include headache, nausea, dizziness, weakness, shortness of breath, low blood pressure, diarrhea, unusual itching or tingling sensation, constipation, and swelling in the feet and hands. Most of these side effects are generally mild and temporary.

✔️ Quick Suggestions:

• Nebita 5mg Tablet lowers your blood pressure and makes it easier for your heart to pump blood around your body.
• Lowering high blood pressure helps prevent stroke and heart attack.
• It may cause dizziness. If this happens to you, get up slowly when rising from a sitting or lying position.
• It can hide symptoms of low blood sugar if you are diabetic. Monitor your blood sugar levels regularly.
• Do not stop taking Nebita 5mg Tablet suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.

✔️ Hypertension

High Blood Pressure, also known as Hypertension, is a common and serious medical condition in which the force of the blood against the walls of the arteries is consistently too high. It is often referred to as the "silent killer" because it can damage the body for years before symptoms become noticeable. Here are some key points about high blood pressure:

Blood Pressure Levels: Blood pressure is measured in millimeters of mercury (mm Hg) and is expressed as two numbers: systolic pressure over diastolic pressure. Normal blood pressure is typically considered to be around 120/80 mm Hg. Hypertension is usually defined as having a consistent reading of 130/80 mm Hg or higher.

Risk Factors: Several factors can contribute to the development of high blood pressure, including genetics, age, diet, lifestyle, and underlying medical conditions. Family history, obesity, a high-sodium diet, lack of physical activity, smoking, excessive alcohol consumption, and chronic stress can increase the risk.

Complications: Untreated or uncontrolled high blood pressure can lead to various health complications, including:

• Heart Disease: Hypertension can strain the heart, leading to conditions like coronary artery disease, heart failure, and heart attacks.
• Stroke: High blood pressure can damage the blood vessels in the brain, increasing the risk of stroke.
• Kidney Damage: It can affect the blood vessels in the kidneys, potentially leading to kidney failure.
• Vision Problems: Hypertension can damage the blood vessels in the eyes, causing vision problems and even blindness.
• Aneurysms: Weakened blood vessels can develop bulges (aneurysms), which can rupture and be life-threatening.

Symptoms: Hypertension is often asymptomatic, meaning it may not present any noticeable symptoms for years. This is why regular blood pressure checks are crucial. In some cases, people with high blood pressure may experience symptoms such as headaches, dizziness, nosebleeds, changes in vision, chest pain, weakness, and shortness of breath. However, these symptoms are not specific to high blood pressure and can be associated with other conditions.

Diagnosis: High blood pressure is typically diagnosed through blood pressure measurements. It's important to have your blood pressure checked regularly, especially if you have risk factors or a family history of hypertension.

Treatment: Lifestyle modifications are often the first line of defense against high blood pressure. These may include dietary changes (reducing sodium intake, adopting a heart-healthy diet), regular exercise, weight management, quitting smoking, and stress reduction techniques. In cases of more severe hypertension, medication may be prescribed by a healthcare provider.

Prevention: Adopting a healthy lifestyle from an early age can significantly reduce the risk of developing high blood pressure. This includes maintaining a balanced diet, engaging in regular physical activity, limiting alcohol consumption, avoiding tobacco products, and managing stress.

Regular Check-ups: Regular check-ups with a healthcare provider are essential for monitoring blood pressure and overall cardiovascular health, even when no symptoms are present.

✔️ Pharmacology

• Pharmacodynamics: Nebita 5 contains Nebivolol, which is a β-adrenergic receptor blocking agent. It has high selectivity for β-1 receptors and also has a nitric oxide-mediated vasodilatory effect.
• Pharmacokinetics: Nebivolol is metabolized by various routes, including glucuronidation and hydroxylation by CYP2D6. The active isomer (d-Nebivolol) has an effective half-life of about 12 hours in extensive metabolizers and 19 hours in poor metabolizers.

✔️ Dosage & Administration of Nebita 5mg Tablet

• For hypertension, the recommended dose is 5 mg daily. Elderly patients should start with 2.5 mg daily which can be increased to 5 mg if necessary.
• In heart failure, the initial dose is 1.25 mg once daily, which can be increased at intervals of 1–2 weeks to 2.5 mg once daily, then to 5 mg once daily, and up to a maximum of 10 mg once daily.

✔️ Interaction

• Nebita 5 should be used with caution when other myocardial depressants or AV conduction inhibitors are used concurrently, such as certain calcium channel blockers or antiarrhythmic agents.
• It should not be combined with other β-blockers.
• CYP2D6 inhibitors (e.g., quinidine, propafenone, fluoxetine) should be used with caution when co-administered with Nebita 5.

✔️ Contraindications

Nebita 5 is contraindicated in several conditions, including severe bradycardia, heart block greater than first degree, cardiogenic shock, decompensated cardiac failure, sick sinus syndrome, severe hepatic impairment, and hypersensitivity to any component of the product.

✔️ Pregnancy & Lactation

The use of β-blockers like Nebita 5 during pregnancy may lead to intrauterine growth restriction, neonatal hypoglycemia, and bradycardia, especially in cases of severe hypertension. Close monitoring of infants is advised if β-blockers are used close to delivery. Nebita 5 is not recommended during breastfeeding due to potential toxicity risks.

✔️ Precautions & Warnings

• Sudden cessation of Nebita 5 treatment should be avoided in patients with coronary artery disease, as it may lead to worsening angina, myocardial infarction, and ventricular arrhythmias.
• Patients with compensated congestive heart failure should receive Nebita 5 with caution, as β-blockers can worsen heart function.
• Patients with bronchospastic diseases should not receive Nebita 5.
• Care should be taken during anesthesia and major surgery if Nebita 5 is continued perioperatively.
• β-blockers may mask some signs of hypoglycemia in diabetic patients.
• Nebita 5 may mask clinical signs of hyperthyroidism.
• Caution is advised in patients with peripheral vascular disease.
• When used with non-dihydropyridine calcium channel blockers (e.g., verapamil, diltiazem), monitoring of ECG and blood pressure is recommended.

✔️ Storage Conditions

Store Nebita 5 in a cool and dry place, protecting it from light and moisture. Keep it out of the reach of children.